Combining next generation qPCR technology with state of the art liquid handling hardware. The Myra+ is an automated molecular instrument ideal for any lab or researcher.
So effortless you won’t even notice it. A perfectly seamless workflow between the Myra liquid handling system and Mic cycler for qPCR. Run Myra+ instruments from the same one user interface. No exporting or importing of sample names required. Just setup, run, and analyse all in one location. Simplified solutions for standard laboratory qPCR processes available at the click of a button. Calibrate Myra+ at the click of a button. No more sticking your head under the hood and eye balling the positions. Myra+ does it all for you.
Myra Liquid Handling + Mic qPCR = Myra+
Increased efficiency -> true seamless workflow from setup to analysis
Accurate results -> the Mic qPCR instrument provides precise and reliable date, while the Myra liquid handling system reduces the risk of human error in sample preparation
User-friendly -> real plug and play hardware and intuitive software, designed with the end user in mind
Cost-effective -> competitive pricing enables entry into complete automation coupled with minimal service costs
Compact footprint -> saves on valuable lab space without compromising performance
Sample Prep
Myra+ is equipped to handle your sample preparation needs, whether you’re using standard magnetic-based extraction methods or going directly to PCR. The device is versatile enough to process various sample formats. For samples that include swabs, Myra+ is uniquely designed to prevent collisions by automatically pushing the swab aside, ensuring smooth operation.
Open platform
There's no need to be confined to costly micro-fluidic cartridges. Experience flexibility with your assays and protocols with Myra+. Features include:
Vortex mixing
Multi-tube aspiration
Film piercing
Extensive consumable library
Lyophilized reagent compatible
V-caps
BMS proprietary V-cap tubes simplify the process of loading qPCR reactions directly into the on-deck Mic cycler. The design uses centrifugal force to push the liquid through an aperture in the cap and into the tube, beneath the pre-filled oil, ensuring efficient and accurate sample processing.
Intuitive software
The Myra+ boasts software that stands out from other automated platforms. For standard lab operations such as qPCR, an intuitive UI enables easy setup, running, and analysis. Create your own custom protocols using our protocol development function. Flexibility without the complexity. LIMS compatibility, user permission levels, and automated analysis functions. 21 CFR part 11 compliant.
qPCR runs
Samples and reactions are loaded directly into the V-cap tubes within the on-deck Mic qPCR cycler. The system is designed to monitor for the presence of tubes and prevent the loading of tubes that might contain the previous run reactions, thereby avoiding contamination issues.
Accessories
Most of the SBS positions feature deep sockets, accommodating deeper wells and longer tubes. We offer a variety of adaptors to fit numerous tube and plate types. BMS's in-house 3D printing capabilities allow them to customdesign new block types to fit unique tubes or plates.
Tips
Reduce the number of times you need to swap out tips with the 384-well rack 50 µl tips. This also helps reduce the space on the deck to allow more space for other plates. These tips improve accuracy and precision for smaller volumes and reduce tip retention. They also afford better position precision for smaller tube openings.
Pressure level sensing
Myra+ uses pressure sensing to detect the liquid level. This reduces the risk of detecting bubbles and being affected by static. There’s also the convenient truth of not having to pay for expensive conductive tips. Further, the head can detect the level of aspirate and dispense giving more accurate feedback on the pipetting during a run.
Software
A dynamic design with style and function. Unlike any other for a liquid handling system. Configure samples and assays, layout your deck and then start Myra+. One setup – one instrument. So easy. Set it up yourself or let Myra+ figure it out for you. With a custom mode for creating your own setup to a fully automated setup using the intelligent option, we’ve got you covered.
Assay creation
Creating assays up front makes life easy for future runs. The assays contain all the information to prepare an experiment such as reaction components, thermal profiles and analysis options. The last two being very useful to integrate with the Mic cycler. Using clever logic embedded into the assay design ensures you never miss critical elements of the setup.
Reactions setup
No longer do you need to configure a robot specific run setup. Simply setup your qPCR run using a format we are all familiar with. Editable tables allow you to easily setup multiple assays and runs along with all the information required to achieve comprehensive analysis of your data. The software continually verifies the setup details are consistent to ensure it all works smoothly.
Accessories
The Myra+ comes with a comprehensive list of accessories, supporting most tubes and plates available on the market.
Calibration
Eye can do it. With a world first integrated high precision camera, achieving calibration on a liquid handling system has never been this easy. Simply click to the middle of the tube image, and let the software do the rest.
Only calibrate what you need. Why spend all day calibrating tubes you won’t even use. The Myra+ software will only require calibration of tubes that are in use. All calibration is recorded to the robot so no need to worry about doing it all again if you change computers or need to exchange the pipette head.
Performance
The key to excellent data starts with Accuracy and Precision. Accuracy is the ability to achieve the right value. Precision is the ability to reproduce the same value. For automated qPCR setup, you need to be able to do both – really well. The Myra+ can. The proof is in the results.
Precision
Means sample repeatability. With an automated pipetting precision of 5% CV at 1 µl, the Myra+ robotic pipette will enhance your qPCR repeatability. Whether it’s for your gene expression studies or MDx, you will be confident in the data when setting up on the Myra+.
KRAS human genomic DNA target. 10,000 copies per reaction. 48 replicates setup using 1 µl of template per 25 µl reaction. Cq = 19.23 | σ = 0.05 | Δmax-min= 0.25 | CV = 0.3%
Repeatability
Even at low copy number. Maintain confidence in your data even when you are working with samples that are influenced by the unavoidable Poisson distribution. The Myra+ automated qPCR setup ensures that the only significant bias in your experiments comes from the probability of aspirating the template and not the performance of the automated pipettor.
KRAS human genomic DNA target. 100 copies per reaction. Repeated three times. 48 replicates setup using 1 µl of template per 25 µl reaction. Cq = 25.35 | σ = 0.11 | Δmax-min= 0.60 | CV = 0.4%
Precise every time
Reproducible results to ensure experimental integrity. We know that the most important part of any scientific work is being able to reproduce your data. With the Myra+, that’s exactly what we aim for. Achieve equivalent experimental setup each time, every time. Even when working with very low copy numbers.
KRAS human genomic DNA target. 100 copies per reaction. 48 replicates setup using 1 µl of template per 25 µl reaction. Cq = 25.39 | σ = 0.11 | Δmax-min= 0.65
Accuracy
Without compromising precision. Myra+’s automated pipetting accuracy is specified to less than 10% for a 1 µl volume. But this does not come at the cost of reducing pipetting precision. BMS's world class pipetting head combined with low liquid retention tips, ensure best in-class liquid handling from a small and compact automated pipetting system.
Capricious gene. 7 point, 10 fold dilution series of the template run in replicates of 4. E = 97% ; R2 = 0.9999
Accuracy and precision maintained
Even at the extreme ! Push the limits of your automated qPCR. A 1.2 fold dilution series is now the norm, not the exception when using the Myra+. With Myra+’s amazing pipetting accuracy and precision combined with Mic’s incredible temperature uniformity ; uncommon has become routine.
Capricious gene. 8 point, 2 fold dilution series of the template run in replicates of 4. E = 96% ; R2 = 0.9993
The art of accuracy and precision
Be creative with your lab automation. With a robotic liquid handler capable of high pipetting accuracy and precision – we though we would be a little creative. So BMS decided to pipette a complex patterned dilution series to add a touch of flair to the already good looking robotic pipette. The result speaks for itself.
A complex pattern of various dilution factors from 10 fold to as low as 1.2 fold. E = 98% ; R2 = 0.9998
*coming soon
Automated qPCR setup
Standard applications like qPCR are built into the software to allow for quick setup. Setup your assays including run profiles and analysis. Myra+ can be configured to setup qPCR reactions in two different ways, depending on your unique laboratory settings:
1. Sample Prep and qPCR Setup is a feature that simplifies your complete workflow setup. The software automatically creates reactions based on user-defined sample input. The sample prep section means you can create a workflow from sample to reaction in only a few simple steps.
2. Reaction Driven qPCR Setup is a flexible option allowing users to create a customised reaction plate based on a desired sample order. Templates can be saved to facilitate routine work, then sample information can be simply imported from a .csv file.
Cycler
Temperature accuracy
±0.25°C
Temperature uniformity
±0.10°C maximum
Ramp rates
Heating : 5°C/s, cooling : 4°C/s
Temperature input range
35 – 99°C
Detectors
Photodiode per channnel
Excitation sources
High energy light emitting diodes for each channel
Combining next generation qPCR technology with state of the art liquid handling hardware. The Myra+ is an automated molecular instrument ideal for any lab or researcher.
Features :
Precise liquid handling robot
Accurate qPCR cycler on deck
Compact size
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